Abstract: With the successful recent launch of VS015 mission, Galileo, The European Satellite Navigation System, can now count of a fleet of 13 operational satellites. After the initial delays and issues that affected the mission schedule, the Galileo system is now deployed with full ground segment support and full service capability will be declared soon. Two ground control centers, one in Fucino, Italy and one in hoberpraffenhfen, Germany, monitor and control both the mission data and space operations. Several sensor stations acquire, monitor and track the Galileo signals all over the globe. 5 uplink stations connect the ground segment to the space segment. Galileo will operate 4 different services with its signal, and specifically the open service (OS), The Commercial Service (CS), The Public Regulated Service (PRS) and Search and Rescue Service (SAR). The seminar will cover both the history in the system design, the challenges, the current status and how and when Europe will be able to use Galileo in an operational context. Furthermore, the seminar will discuss the innovation of such system with respect to GPS, the main differences, and the global political and technical challenges in the Global Navigation Satellite Systems scenario. As a conclusion, the research and industrial opportunities of Galileo will be discussed.